How Does IUI Work? The Complete IUI Procedure Step By Step

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How Does IUI Work? The Complete IUI Procedure Step By Step

How Does IUI Work? The Complete IUI Procedure Step By Step

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Infertility issues are rising among females because of age, physical problems, hormone problems, and lifestyle or environmental factors. Most of these factors are not under our control, and if you are also among the women who have infertility, you can go for Assisted Reproductive Technique. There are many Assisted Reproductive Techniques like IUI works and gives successful pregnancy to female fertility issues. IUI has brought hope into the lives of many women by giving them the opportunity to get pregnant. The success rate of intrauterine insemination when the blockage is closest to the ovary is 11.7%, and when the blockage is closest to the uterus, the success rate is as high as 38.1%. 

What Is Intrauterine Insemination? 

Intrauterine insemination (IUI) is a type of fertility treatment. In this, sperms are directly placed into the woman’s uterus through the cervix, which helps healthy sperm to get closer to the egg. In IUI, when a woman is ovulating, sperm is directly put into her uterus, which shortens the time and distance sperm has to travel, making it more hospitable to fertilize the woman’s egg. In IUI, when the sperm is placed into the uterus, it is expected that it will travel into the fallopian tube and fertilize an egg, resulting in pregnancy. IUI is chosen by most couples when they have the following issues:

  • Donor sperm: When the sperm quality of the male partner is not viable for reproduction or a single woman wants to get pregnant, or if a couple does not wish to transmit a genetic disorder to their child, they need a sperm donor. IUI is the most common procedure used to achieve pregnancy with donated sperm.
  • Unexplained infertility: When the doctor could not determine the reason for infertility, IUI is the first procedure the doctor recommends.
  • Endometriosis-related infertility: Endometriosis is a condition in which the tissue that normally lines the uterus grows outside the uterus. In such cases, the first approach usually is performing IUI and using medications to achieve a good-quality egg.
  • Mild male factor infertility (subfertility): When the quality of your partner is below average, then IUI is the first procedure a doctor suggests because when preparing sperm for the procedure, they separate highly motile, normal sperm from those of lower quality.
  • Cervical factor infertility: If the cervical mucus is too thick, it can hinder the sperm’s journey. In IUI, sperm bypasses your cervix, depositing sperm directly into your uterus and increasing the number of sperm available to meet the awaiting egg. That’s why IUI is a good option for women with cervical factor infertility.
  • Ovulatory factor infertility: In the case of Ovulatory factor infertility, IUI is the first treatment approach considered by doctors.
  • Semen allergy: When a woman has an allergy to the proteins present in semen, then also IUI is the best approach for the treatment. IUI can be effective since before inserting the semen; doctors can remove the proteins from the semen.

How is IUI Beneficial?

With medical science progressing, now we have many Assisted Reproductive Techniques. Let us see why Intrauterine insemination is better than other Assisted Reproductive Techniques.

  • IUI is cheaper when compared with IVF, ICSI.
  • It is less invasive as in this process, only sperm is placed into the uterus, unlike IVF.
  • Sperm quality enhances because of the washing procedure. In IUI, prostaglandins, infectious agents, antigenic proteins, non-motile spermatozoa, immature germ cells, etc., are removed for a better quality sperm. 
  • This process is less painful and does not require anesthesia.
  • IUI increases the chances of getting pregnant more than the regular sex.
  • IUI is gentler on the body than IVF. IVF might deteriorate the quality of the egg and could be harsh and aggressive on your body.
  • There are fewer chances of Ovarian Hyperstimulation Syndrome (OHSS).
  • It is a great way to see how a woman’s body will react before going to IVF without wasting an ovulation cycle.

Step-by-Step Guide for IUI Process 

If you are thinking of getting IUI done, there might be many questions about the procedure. In order to answer that let us go through the step-by-step process of IUI.

  • The first step is to find the perfect timing for the insemination of sperm while the woman is ovulating. In case the woman has already been through an unsuccessful IUI or has a problem with ovulation, oral or injectable medications are given to the woman to stimulate the growth and maturation of her eggs. 
  • When a woman is ovulating naturally, she has to keep track of her ovulation cycle to go to the doctor within 24-36 hours for further carrying out the IUI procedure. In the case of injectable medications, with the help of AMH, hysteroscopy tests are done every 2-3 days to monitor the ovaries and egg development. Once a ripe egg is present, the woman receives a trigger shot that causes ovulation within about 36 hours.
  • Sperms are washed, and prostaglandins, infectious agents, antigenic proteins, non-motile spermatozoa, immature germ cells, etc., are removed for a better quality sperm. Then the best quality sperm is chosen for the process.
  • The doctor inserts the sperm into the patient’s uterus using a long thin tube called a catheter in medical terms. It is inserted into the uterus through your vagina, passing through your cervix area. The tube then releases the sperm into your uterus and hopes to successfully carry out its further journey towards the eggs.
  • The last step is to hope for the best and take a pregnancy test after a few days of insemination.

How to Prepare for the IUI Procedure?

One should keep the following things in mind before going for Intrauterine insemination.

  • Avoid stress because it could have an impact on the success rates of treatments.
  • Take a healthy diet.
  • Avoid ejaculation for three days because of the volume of semen and the amount of sperm matter during IUI. 
  • One has to go for the test of sperm quality and if the male candidate has oligospermia. Then he should opt for good food that increases sperm count.


Intrauterine insemination is a good treatment if you can not get pregnant naturally. Before trying any other Assisted Reproductive Technique, one should try IUI. IUI success rates are reasonable and treatment is affordable than other artificial reproduction techniques. If you are looking for a good fertility clinic, then your search is over. Aastha Fertility Care provides the best IUI treatment and comes with the best success rates in India. They take care of your every need and make your journey to pregnancy very smooth.

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