Reasons of Recurrent IVF Failure and How Can Risk be Reduced

With increasing cases of sterility, IVF has become a more accepted artificial reproductive technique that claims a safe and successful pregnancy. IVF started as a very basic artificial pregnancy solution 43 years ago in 1978, and it has become a strong option for infertile couples with modern laboratories, equipment, and more skilled specialists. IVF treatment is continuously scaling new records of its success rate and is tapping all the possibilities.

Even then, it may not always be accurate, and it may not be possible every time your IVF treatment is successful. That’s why some couples undergoing IVF treatment have a recurrent failure, which is emotionally and financially.

Recurrent IVF failure is devastating for the couple as well as the fertility centre. Aastha Fertility Care Can Help. 

What are the Reasons for Recurrent IVF Failure

Recurrent IVF failure refers to cases where women have had three failed in vitro fertilization attempts. The quality of the embryos created through this procedure can be good or bad. In the case of a good embryo, the woman has a 75 percent chance of getting pregnant, but if the embryos do not survive that long period during which it is kept in the lab, the chances are high that she’ll have to undergo another round of IVF treatment.

According to statistics, 40% of women who take fertility drugs have failed to give birth after 3 IVF attempts, and an additional 20% may fail at the fourth try. The inability to achieve a successful pregnancy after three IVF attempts can be due to several reasons.

Poor embryo quality was identified as the most common cause of repeated IVF treatment failures in women. IVF experts say that the embryo may appear completely healthy, but it has some genetic properties, due to which it can be chromosomally unfit for implantation. Poor egg quality Endometriosis are other reasons for recurrent failure.

However, there may be other causes of recurrent failure that impede embryo implantation, including –

  • Uterine fibroids (noncancerous growths in the uterus) 
  • Uterine polyps (noncancerous growths on the wall of the uterus) 
  • Intrauterine adhesions (when scars form on the uterine wall after an infection, which can make it harder for embryos to implant)
  • Intrauterine infection(Infection of the fallopian tubes and ovaries) 

In addition male factor infertility, immunologic implantation failure (when the body’s defense system attacks the embryo), and genetic abnormalities. 

But the good news is that a few treatment options can help you maintain your fertility and possibly reverse recurrent pregnancy loss.

Doctors at Aastha fertility care were taken aback for the reason for which these women were not able to conceive.  Our IVF treatment is one of the most advanced medical procedures, and it is successful in the majority of the cases. 

Our experienced IVF specialists understand specific reasons for recurrent IVF failure and every aspect before embarking on the IVF or IUI process

When to Try Again After IVF Cycle Failure

These days, not everyone is lucky enough to have a successful first IVF cycle, and if the woman is in her thirties or forties, the  IVF success rate naturally drops. And not everyone can go through multiple IVF cycles because the process is complicated and financially unbearable, so IVF failure is very distressing.

You should discuss with your doctor to avoid recurrent failure and take steps to prevent further loss. You should take enough time to move on to the next cycle and jump into it by organizing by all means. 

Keep a positive attitude towards your treatment as hormones will also be a participant, and as far as retry is concerned, one can go for another IVF cycle after a gap of one month.

If a couple has already tried three cycles of IVF and the attempt has been unsuccessful, it is best to get re-evaluated.

How to Reduce the Recurrent IVF Failure

The best way to avoid recurrent failure is to start working on it early. There are many natural and technical ways to prevent recurrent IVF failure by which you can minimize the risk of loss.

  • Before the treatment month, you should emphasize healthy eating habits and avoid overeating canned and junk food. Read food that can help to increase sperm count in men naturally.
  • If you are overweight or suffer from PCOS, you will need to lose weight four months before IVF treatment because doctors consider a low BMI a sign of IVF success. Do not exercise too much; just control it by making changes in the diet.
  • Be sure to get your Thyroid-Stimulating Hormone (TSH) level checked because an abnormal TSH level can cause a miscarriage.
  • Quit alcohol and smoking entirely before IVF treatment


So in this way, you can reduce the risk of recurrent IVF failure and wish for a healthy baby, although a successful IVF treatment also depends on many other factors which the doctor can better tell you. Dr. Namita Kotia is an experienced IVF specialist and gynecologist you can consult. She is the director of the technically advanced Aastha Fertility Center, which offers the best of all fertility treatments.

Picture of Dr Namita Kotia

Dr Namita Kotia

Dr. Namita Kotia (IVF specialist in Jaipur) attained her Master’s in Obstetrics and Gynecology from S.N. Medical College, Jodhpur affiliated to University of Rajasthan in 1997. She has more than 10 years experience in field of Assisted Reproductive Technology (ART). Presently at Aastha Fertility Care Dr. Namita along with her team is providing complete infertility work up and treatment options under one roof. Her aim is to provide proper guidance and treatment to Infertile couples at AFFORDABLE RATES. She is life member of Indian Academy of Human Reproduction (IAHR), Indian Society for Assisted Reproduction (ISAR), Federation of Obstetrics and Gynecology Society of India (FOGSI) and Jaipur Obstetrics Gynecology Society (JOGS). She has a number of publications in various journals and presentations at state and National level conferences to her credit. Dr. Namita is also recipient of best paper presentation viz “Diagnosis of Congenital Mullerian anomalies by three dimensional Transvaginal Sonography” awarded at “Kishori” Conference in Jodhpur (2000).

Leave a comment

Are you facing Infertility Problems?

Book your Consultancy Call today!