Side Effects of IVF Treatment

Side Effects of IVF Treatment

Side Effects of IVF Treatment


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When it comes to fertility treatment, there are a number of options available for couples struggling with infertility. Ovulation induction and intrauterine insemination (IUI) are some of the most common treatments, but In Vitro Fertilization (IVF) is the best option for those who have tried everything else but failed to achieve pregnancy. IVF treatment can help couples have their biological child. It involves a controlled ovarian stimulation in the lab using the woman’s eggs and the man’s sperm.

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Today, IVF is considered a successful infertility treatment when taken under the supervision of an experienced doctor. But there is no doubt that IVF procedures can be very stressful for some couples. Though most couples look forward to this treatment because it is their last hope to have a baby, there are many side effects of IVF treatments that people are unaware of, which we will discuss in this article. 

When it comes to IVF Treatment without any side-effects, Aastha Fertility care has a dedicated team of doctors, physicians, and a well-equipped lab that is able to provide the best treatments for patients. Our doctors have undergone regular training in advanced IVF techniques, minimization of side-effects and genetic diseases.

What is In-Vitro Fertilization

IVF treatment is a process that has been around for more than three decades now. 

IVF procedures have been used for decades to help millions of couples when other infertility treatments have failed. In-Vitro Fertilization is a procedure where a man’s sperm and woman’s eggs are combined outside of the body in a laboratory dish to form an embryo by fertilization. One or more embryos are then transferred into the woman’s uterus using a plastic catheter (tube). 

IVF is a unique process that has brought a lot of joy to many families worldwide. However, the treatment should not be taken lightly. Like with any medical procedure, there are some side effects, both long and short-term, involved in the treatment. In addition to the risk of multiples, there are many other associated risks to in vitro fertilization. 

What to Expect When You’re Having IVF Treatments?

1. Body changes

Women sometimes gain weight throughout IVF treatments, and hormone injections impact weight and appetite. Based on how many eggs grow or if you have modest ovarian hyperstimulation, your stomach may feel bloated and your clothes tight. If you are gaining weight that is beyond control, visit your doctor. 

2. Increased hunger

Some individuals may experience increased hunger. Some drugs may boost appetite, but it’s usually emotionally driven. No matter what, always eat healthily.

3. Gastrointestinal changes

Constipation and loose stools are frequent IVF complaints. To address digestive difficulties, drink plenty of water and consume fiber-rich foods.

4. A journey full of surprises

IVF procedures vary from patient to patient. Don’t be astonished if your appetite increases throughout treatment; do not be shocked if you require more sleep each night. These experiences are normal. 

In-Vitro Fertilization (IVF) Side Effects at Each Stage

Stage 1: Suppression (Pause and Prepare) 

The first phase involves calming the ovaries using Oral contraceptives. Regular menstrual cycles have follicles mature at varying rates. And some are slower, and others are faster. Their size coincides with their maturation; eventually, one dominant follicle will win out. Yet, this shouldn’t happen with IVF. The main aim is to mature all eggs at once to increase egg output during retrieval. Hence, OCs are used.

Side effects are minor if detectable. Examples:

  • Breast pain
  • Nausea
  • Mood changes
  • Spotting

Stage 2: Stimulation 

The next phase involves injection since oral medication alone isn’t enough. In IVF, the more mature eggs you produce, the better. Injections are given for 8-14 days to stimulate egg production, and Slow-maturing follicles prolong the stimulation period.

Side effects include:

  • Headaches
  • Meltdowns
  • Injection-site bruising
  • Nausea
  • Bloating
  • Bruising

Stage 3: The Egg Retrieval 

Egg retrieval (done under anesthesia) is the third stage where egg removal is done from the follicles. 

Side effects include:

Egg retrieval involves surgery. Therefore, you’ll need anesthesia, which has effects, and most women have moderate side effects that disappear within a few days. These include:

  • Spotting
  • Soreness
  • Fatigue
  • Nausea
  • Bloating
  • Cramping
  • Vomiting 

Stage 4: The Embryo Transfer

Fresh or thawed blastocysts are transferred during an embryo transfer.

Apart from pregnancy, embryo transfer has some side effects.

Embryo Transfer Side Effects:

  • Bruising
  • Bloating
  • Cramping
  • Fatigue
  • Constipation
  • Injection-site bruising

Long-Term Side Effects of IVF Treatment 

1. Ovarian Torsion

Ovarian is a condition when an ovary twists around the ligaments that hold it in place. It has been described as the most painful experience by women. Ovarian Torsion occurs when there is a problem with the ligaments that support the ovary and cut off the blood supply. 

Various symptoms are associated with ovarian torsion, including sudden onset of severe pain, swelling in the abdomen, nausea, vomiting, fainting, or even convulsions. Here, at Aastha Fertility, we make the patient undergo various tests before designing the treatment and medication set to minimize even the slightest possibility of Ovarian Torsion.  

2. Vision Problems 

Although visual disturbances are relatively uncommon in IVF patients, they can occur after a cycle of clomiphene or gonadotropins stimulation. Visual disorders such as palinopsia (phosphenes) or afterimages can affect a patient’s vision. This problem occurs because of increased estrogen levels, linked to acute alterations in the visual system.

Gynecologists and infertility experts must educate their patients regarding these possible side effects to be aware of vision problems. At our clinic, we test every female’s corneal biomechanics to eliminate the chances of palinopsia and other vision-related problems and protect his vision during the IVF procedure.

3. Ovarian Hyperstimulation Syndrome ( OHSS)

Ovarian hyperstimulation syndrome or OHSS is a condition arising from the excessive release of the stimulating follicle hormone (FSH) in women undergoing In vitro fertilization (IVF). The syndrome refers to a set of symptoms that may occur soon after ovarian stimulation for an IVF cycle. 

These symptoms can vary widely from mild to severe and result in pain and discomfort. OHSS is a potentially dangerous condition that could be fatal to the patient. Causes of OHSS include female body characteristics, medications, egg donation, and genetics.

Doctors at Aastha perform hysteroscopy and AMH blood tests in order to examine pelvic pain and issues with miscarriage in a female. Mature follicles are frozen at a proper temperature to make ovaries rest. The process is then delayed until the patient’s body is ready for the process again.

4. Multiple Pregnancy 

IVF increases the risk that you might deliver more than one infant, known as twins or multiples. In addition, IVF with multiple pregnancies is associated with fewer complications compared to providing a singleton. Premature delivery, low birth weight, and congenital anomalies are more common in identical twins than in singletons born by IVF.

Depending upon the patient’s choice, the gynecologists at Aastha transfer a single embryo to the female’s uterus to attain a single pregnancy. Sonographies are also done at every step of the process to ensure singlet. 

5. Ectopic Pregnancy 

An ectopic pregnancy occurs when a fertilized egg implants outside the uterus, the most commonplace being in the fallopian tubes. Without proper treatment, an ectopic pregnancy can result in a tubal rupture and is life-threatening for the mother.

Unlike other clinics, doctors at our clinic offer special transvaginal ultrasound scans to determine Ectopic Pregnancy at an early stage. We use medicines like Methotrexate and surgical processes like Salpingostomy for treating EP in females. 

6. Cancer

Although there were reports earlier that certain drugs used for ovarian stimulation may cause ovarian tumors, more recent research does not support these findings. Women who have undergone IVF have no increased risk of breast, endometrial, cervical, or ovarian cancer. 

And if a female has cancer, fertility preservation by Aastha Fertility Care is a good way to save your eggs if you want to plan a baby in future. 

Short Term Side-Effects of IVF Treatment

1. Anxiety 

IVF can be emotionally and physically draining. Couples going through the process may find that learning about the process, support from counselors, lawyers, family, and friends will help them get through the ups and downs of infertility treatment. 

We have a highly-professional team of psychologists and counselors to support you during the entire process from starting till the end. Even after the treatment, we check on our patients to ensure they are not stressed.  

Recurrent IVF failure is also a reason why some females are stressed about getting success in the next IVF cycle. 

2. Mood Swings 

Given that infertility is a sign of hormonal and reproductive imbalance, fertility medication’s most common side effects are headaches, nausea, mood swings, and bloating. Seek instant medical help and treatment when you face such issues.

3. Premature Delivery 

Research suggests that combining the sperm and egg in a laboratory dish and then transferring an embryo or embryos into the woman’s uterus slightly increases the baby’s risk of being born early or with low birth weight.

Premature delivery is not a severe issue and does not harm the baby. The premature baby at our clinic is taken under observation for a few days to provide special care and the mother. For us, the health of the baby and the mother matters the most. 

4. Allergic Reactions 

Women planning to get pregnant in the near future have nothing to worry about. The chances of allergic reactions to fertility drugs are rare. However, as with any medication (or food), a reaction is possible. Suppose you have a family history of allergic reactions. In that case, you may wish to discuss the matter with your OB-GYN and infertility doctor to determine whether or not you are at higher risk for an allergic reaction to fertility drugs and the process. Doctors at Aastha Clinic designed the IVF procedure after asking about past medical issues and allergic reactions to prevent allergies or any type of body reaction. 

Aastha Fertility Care- The Right Choice For Treating Infertility 

One of India’s leading fertility care clinics, Aastha Fertility Care, is the best option for IVF treatment. We ensure the highest success rates and lowest miscarriage in all IVF treatments performed in advanced laboratories under expert surveillance. The clinic is becoming a popular choice among patients from India and places like Australia, the Netherlands, and the Far East

Aastha Fertility Care brings together the convenience of state-of-the-art technology with the warmth and compassion of a small clinic under one roof. The treatment combines advanced methods with time-tested practices to give you the best chance at conceiving a baby quickly and naturally without any side effects.

We make sure that every couple who comes to our clinic gets successful parenthood with happy smiles and no worries.  

Frequently Asked Questions

  1. Can IVF cause any health issues?
    Children born by Test Tube Baby are somehow a little more prone to health issues in future. The  female patients who have taken IVF are at a risk of getting high blood pressure along with OHSS. 
  2. Does IVF damage your ovaries?
    Yes, a female who has taken an IVF treatment can develop OHSS. Though the chance to get such a problem is rare, if it happens, it will damage your ovaries
  3. Is In Vitro Fertilization Linked to Increased Risk of Birth Defects?
    In vitro fertilization increases the risk of musculoskeletal, eyes, reproductive organs, heart defects, nervous system deformities, premature births, and low birth weight. Maternal and paternal variables, as well as IVF, appear to pose risks.
  4. What Are the Side Effects of IVF Medications? 
    The side effects of IVF Medications include:
    – Hot flashes
    – Headaches
    – Blurry Vision
    – Nausea
    – Chances of multiple births
    – Cervical mucus changes.
  5. What are the Side Effects and Risks of IVF Treatment on Mother and Baby?
    – Babies born with birth defects
    – Ectopic Pregnancy
    – Multiple Births
    – Miscarriages
    – Preterm birth
    – Low birth weight
    – Heavy Uterine Bleeding
    – Some reactions to fertility drugs
  6. Does Hormone stimulated during IVF have any side effects?
    Some possible side effects of Ovarian Stimulation include:
    – Because numerous eggs are released, there is a greater likelihood that several eggs may attach to the uterus and result in multiple babies.
    – Increased rates of miscarriage and early birth
    – Breast soreness, redness at the injection site of hormones, and swelling.
    – Mood fluctuations and depression
    – Ovarian hyperstimulation syndrome may result in enlarged ovaries, stomach discomfort, and bloating.
  7. What Are the Side Effects of IVF Medications? 
    Some of the side effects of IVF Medications are bloating, headache, upset stomach, breast tenderness, hot flashes, and mood swings.

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