Symptoms of Failed IVF: Factors Contributing To IVF Failure

In-Vitro Fertilisation treatment is a game-changer in the medical industry as it has helped millions of couples struggling with infertility in India to have healthy and happy families. However, it does not mean that all couples treated with IVF have achieved success. According to Aastha Fertility Report on Success Rate for IVF under 35, IVF success rates range between 19% to 27%, depending on maternal age and other factors.  

Still, the IVF industry is flourishing rapidly as its symptoms and risks outweigh the benefits of IVF treatment. According to an article published in the Times of India, Globally, more than 2.5 million IVF cycles are done every year. In India, it is just 2 to 2.5 lakh cycles performed yearly. 

However, when done by a qualified fertility treatment provider, you will have a higher chance of success. Aastha Fertility Centers holds the record for India’s highest IVF success rate, i.e., 30%. 

Nevertheless, as every patient has a unique issue, some factors make a difference in the success potential.

Symptoms of Failed IVF

Signs That Your IVF Process Has Failed

If embryo implantation is not successful, you will notice some symptoms like:

Vaginal bleeding





Mood swings

Breast tenderness

Lower back pain

Symptoms do not always ensure that your IVF cycle has failed. Sometimes, the same symptoms indicate success. That is why you need to take a pregnancy test to confirm the success or failure of the IVF cycle.

Get More Information about – Implantation Symptoms

The test detects the presence of the hCG hormone produced after implanting the embryo in your uterine lining. If no hCG is found in the test, it signals the failure of the process. 

Other ways to determine the failed IVF:

  • No Implantation

Due to improper embryo implantation in the uterus, you will have no pregnancy symptoms like morning sickness or missed periods.

  • Distressed Feelings

IVF failure will result in negative feelings. You will have feelings of disappointment and sadness. 

Remember that not every patient will have these symptoms. So, even with these signs, you need to consult a fertility specialist. Get guidance from the expert treatment providers at Aastha Fertility Center for the best results. 

Significant Factors Contributing To IVF Failure

Pre-Treatment Factors 

Several pre-treatment factors contribute to the failure.

Essential Factors Behind IVF Defeat


As your age advances, it leads to degradation in the quality and number of oocytes.

Antral Follicle Count

This factor is related to anti-mullerian hormones and age. With the natural aging process, you will find decreased AMH values and follicle count. 

Additionally, check out: What is Low AMH Level: Causes & Treatment

Ovarian Reserve 

If you have a low ovarian reserve, it indicates that there are fewer eggs in your ovaries. Your body cannot produce the desired number of eggs to make the IVF cycle successful. 


It is a condition in which tissues near the uterus lining do not grow properly. So, it prevents embryo implantation and progress in pregnancy. 

Furthermore, explore: Thin Endometrium: Causes, Symptoms, and Treatment

Polycystic Ovary Syndrome (PCOS) 

This hormonal issue interferes with the normal ovulation process. So, your ovaries cannot produce eggs. 

Also Read: Types of PCOS in females

Male Factor

Factors related to male infertility prevent the sperm from fertilizing eggs.

Low Sperm Count is one of them. 

Tubal Or Uterine Factors 

Scarring, polyps, and fibroids make embryo implantation challenging. Thus, you may not find proper progress in your pregnancy.

Previous IVF Failure Cases

There may be underlying issues if you have previously failed in your IVF treatment. 


BMI ranging from 19 to 30 is ideal. If it is higher than 30, it results in a low fertilization rate. So, patients may have ovulatory issues. It also increases the risk of miscarriage. Obesity affects men’s reproductive systems also. It raises the estrogen level while lowering testosterone.

Read also: Effect of Estrogen on Women’s Body and Fertility

Post-Treatment Factors 

Some post-treatment factors are responsible for IVF failure.

Toxic Factors 

Those who have habits of consuming alcohol or tobacco may not achieve success in IVF.

Embryo Quality 

It is another factor that interferes with your normal IVF cycle.

Embryos Transferred 

Your IVF treatment’s success depends on how many embryos have been transferred.

Furthermore, explore: Positive Signs After Embryo Transfer

Transfer Timing

Appropriate timing is important while transferring your embryos.


In some cases, the embryo is not implanted in your uterus, leading to failure in the IVF cycle.

Luteal Phase

Progesterone and other medications used for the luteal phase can affect your IVF cycle. 

When Can You Repeat The Treatment After Having A Negative Pregnancy Test?

The standard gap between IVF cycles is 4 to 6 weeks. You should wait until you have a full menstrual cycle after the failed implantation. To learn more about timing, you can consult a fertility specialist.

What To Do To Avoid Failed Implantation?

A few tips for minimizing the risk of failed implantation.

Adjust Your Lifestyle

You should not drink alcohol to maintain your pregnancy. Even your partner must avoid smoking and alcohol consumption to keep the sperm healthy. 

Control Your Weight

Both being underweight and overweight are not suitable for IVF patients.

Identify Underlying Health Issues 

If you have hormonal issues, uterine problems, diabetes, or other diseases, you must start treatment.

Is Failed IVF Common?

According to a study published on igenomix, around 67% of India’s IVF cycles fail for various reasons. Egg quality and quantity, age of females, and sperm quality are some factors contributing to IVF failure. But, with the proper supervision of certified doctors, you can avoid failure. 

Get in touch with the Best IVF Specialists at Aastha Fertility to reduce the chances of IVF Failure

Aastha Fertility is a prominent clinic to provide different fertility treatments. Its dedicated team of IVF Specialists schedules a consultation session to learn about your fertility issues. After diagnosing your condition, certified fertility treatment providers will treat you with IVF or other techniques. Also the IVF treatment cost at Aastha Fertility clinic is an important consideration for couples who are seeking fertility treatments.

Frequently Asked Questions

1. What are the symptoms of IVF failure?

Due to failed IVF, you will have lower back pain, nausea, headache, and other symptoms.

2. Can you still have a period after a failed IVF cycle?

After 2 to 3 months of your IVF failure, you will have a normal period.

3. Can a failed IVF cycle affect future pregnancies?

Yes. Under the supervision and guidance of an IVF fertility treatment provider, you can naturally give birth to a child. But, lack of treatment may lead to miscarriage.

4. Is there any physical pain associated with IVF failure?

Some patients have reported abdominal pain and cramping after IVF failure.

5. How long after the embryo transfer will I know if the IVF cycle was successful?

After two weeks of embryo transfer, you can take a blood test to know whether the cycle is successful.

Dr Namita Kotia

Dr Namita Kotia

Dr. Namita Kotia (IVF specialist in Jaipur) attained her Master’s in Obstetrics and Gynecology from S.N. Medical College, Jodhpur affiliated to University of Rajasthan in 1997. She has more than 10 years experience in field of Assisted Reproductive Technology (ART).Presently at Aastha Fertility Care Dr. Namita along with her team is providing complete infertility work up and treatment options under one roof. Her aim is to provide proper guidance and treatment to Infertile couples at AFFORDABLE RATES.She is life member of Indian Academy of Human Reproduction (IAHR), Indian Society for Assisted Reproduction (ISAR), Federation of Obstetrics and Gynecology Society of India (FOGSI) and Jaipur Obstetrics Gynecology Society (JOGS). She has a number of publications in various journals and presentations at state and National level conferences to her credit.Dr. Namita is also recipient of best paper presentation viz “Diagnosis of Congenital Mullerian anomalies by three dimensional Transvaginal Sonography” awarded at “Kishori” Conference in Jodhpur (2000).

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